What are the dissolution methods for hydroxypropyl methyl fibers?

Hydroxypropyl methyl fiber (HPMC) is a water soluble polymer, which is commonly used to prepare capsules, tablets, cream, etc. in medicine, food and cosmetics. The following are some dissolution methods for hydroxypropyl methyl fibers:

Water dissolution method: HPMC can be dissolved in water at room temperature. Usually, a stirrer or stirring rod is used to gradually add HPMC powder to water and fully dissolve it during the stirring process.

Alcohol dissolution method: Hydroxypropyl Methyl Cellulose can also be dissolved in alcohol. Add an appropriate amount of alcohol to the container, then gradually add HPMC powder while stirring until dissolved.

Mixed solvent dissolution method: HPMC powder can be mixed with some organic solvents, such as ethanol, acetone, etc. Add an appropriate amount of mixed solvent to the container, then gradually add HPMC powder while stirring until dissolved.

It should be noted that high temperatures in the solvent should be avoided when dissolving HPMC to avoid gelatinization or degradation of HPMC. In addition, the solubility of HPMC of different types and grades may vary in different solvents, so in practical applications, appropriate dissolution methods need to be selected based on specific circumstances.